Uncovering spatiotemporal patterns of atrophy in progressive supranuclear palsy using unsupervised machine learning.
William J Scotton,
Cameron Shand,
Emily Todd,
Martina Bocchetta,
David M Cash,
Lawren VandeVrede,
Hilary Heuer,
4RTNI Consortium PROSPECT Consortium,
Alexandra L Young,
Neil Oxtoby,
Daniel C Alexander,
James B Rowe,
Huw R Morris,
Adam L Boxer,
Jonathan D Rohrer,
Peter A Wijeratne
Apr 17, 2023
To better understand the pathological and phenotypic heterogeneity of progressive supranuclear palsy and the links between the two, we applied a novel unsupervised machine learning algorithm (Subtype and Stage Inference) to the...